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Master Specialist Internal Medicine (INT5921)
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Sample Practice Questions

Question 1 FULLY WORKED EXAMPLE

A 58-year-old man with type 2 diabetes and hypertension presents with 3 days of progressive dyspnoea, orthopnoea, and bilateral leg swelling. He reports no chest pain. Vital signs: BP 168/96 mmHg, HR 112/min, RR 26/min, SpO2 89% on room air, temperature 36.8?C. Examination reveals bibasal crackles, elevated JVP, and S3 gallop. ECG shows sinus tachycardia with no ST changes. Troponin I is 0.04 ng/mL (normal

A) Urgent coronary angiography
B) Intravenous furosemide and nitrates ✓ Correct
C) Broad-spectrum antibiotics for community-acquired pneumonia
D) Therapeutic anticoagulation for pulmonary embolism
Explanation:
The deciding finding is the normal troponin with classic signs of acute decompensated heart failure (orthopnoea, S3, elevated JVP, pulmonary congestion on X-ray, and markedly elevated BNP). The clinical picture is heart failure, not ACS, pneumonia, or PE. Intravenous loop diuretics and nitrates are first-line for acute hypertensive heart failure with congestion per ESC guidelines. Coronary angiography is not indicated without ischemic symptoms or ECG changes. Antibiotics are inappropriate as there is no fever, purulent sputum, or focal consolidation. Anticoagulation for PE is not supported as there is no pleuritic pain, risk factors, or RV strain.
References: ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure, European Society of Cardiology
Question 2 TRY IT — TAP AN ANSWER

A 34-year-old woman at 32 weeks gestation presents with 2 days of right upper quadrant pain, nausea, and malaise. She has no prior liver disease. Vital signs: BP 148/92 mmHg, HR 98/min, temperature 37.2?C. Laboratory: ALT 210 U/L, AST 185 U/L, platelets 88 x 109/L, LDH 620 U/L, bilirubin 1.8 mg/dL, creatinine 1.1 mg/dL. Urine protein is 2+ on dipstick. Peripheral blood smear shows schistocytes. What is the most likely diagnosis?

A) Acute fatty liver of pregnancy
B) HELLP syndrome
C) Viral hepatitis A
D) Intrahepatic cholestasis of pregnancy
💡 Pick an answer above to see if you're right — the full explanation unlocks instantly.
Question 3 TRY IT — TAP AN ANSWER

A 72-year-old man with COPD (FEV1 45% predicted) presents with 4 days of increased sputum purulence, cough, and dyspnoea. He has no fever or chest pain. Vital signs: RR 24/min, HR 92/min, SpO2 88% on room air (baseline 92%). Chest X-ray shows hyperinflation without consolidation. He has received amoxicillin for 3 days without improvement. What is the most appropriate antibiotic?

A) Amoxicillin-clavulanate
B) Azithromycin
C) Levofloxacin
D) Doxycycline
💡 Pick an answer above to see if you're right — the full explanation unlocks instantly.
Question 4 TRY IT — TAP AN ANSWER

A 45-year-old woman presents with 6 weeks of fatigue, arthralgias, and a malar rash. She has no oral ulcers or photosensitivity. Vital signs: BP 138/84 mmHg, HR 78/min, temperature 37.0?C. Laboratory: ANA 1:640, anti-dsDNA positive, C3 low, C4 low, urine protein 3.5 g/24h, creatinine 1.0 mg/dL, platelets 210 x 109/L. She has no hematuria or red cell casts. What is the most appropriate next step?

A) Start high-dose prednisone and mycophenolate mofetil
B) Start hydroxychloroquine alone
C) Renal biopsy
D) Start cyclophosphamide pulse therapy
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Question 5 TRY IT — TAP AN ANSWER

A 68-year-old man with atrial fibrillation on warfarin presents with sudden onset of right arm weakness and aphasia. Last known well was 2 hours ago. Vital signs: BP 178/94 mmHg, HR 110/min irregular, glucose 142 mg/dL. Non-contrast CT head shows no hemorrhage. INR is 2.8. What is the most appropriate management?

A) Intravenous alteplase
B) Mechanical thrombectomy
C) Aspirin and admission
D) Reverse anticoagulation with vitamin K and prothrombin complex concentrate
💡 Pick an answer above to see if you're right — the full explanation unlocks instantly.

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Specialist Internal Medicine (INT5921) Questions for DHA Speciality — FAQ

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MedLumen currently has 846+ Specialist Internal Medicine (INT5921) practice questions for DHA Speciality, each with a detailed explanation so you understand the reasoning behind every answer.

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