2026 Question Bank · MRCP(UK) · Royal Colleges of Physicians

The MRCP Part 1 Question Bank
Built for Best-of-Five

AI-adaptive best-of-five practice across the full MRCP(UK) blueprint — including the clinical sciences and pharmacology most candidates under-prepare — with timed mock papers and detailed, guideline-aligned explanations.

804+MRCP Part 1 questions
200Questions in the real exam
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✓ Full MRCP(UK) Blueprint ✓ Best-of-Five Format ✓ Clinical Sciences & Pharmacology ✓ Timed Mock Papers ✓ iOS & Android App
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What Is the MRCP Part 1 Exam?

MRCP(UK) Part 1 is the first of three assessments in the Membership of the Royal Colleges of Physicians examination, run by the Federation of Royal Colleges of Physicians of the UK. It tests how you apply basic and clinical sciences to common and important medical problems — the foundation for higher specialty training in medicine.

It is a written exam of two 3-hour papers, each containing 100 best-of-five (BOF) questions, sat on the same day — 200 questions in total.

💡 The trap most candidates fall into

The clinical sciences and clinical pharmacology components carry real weight but are the areas working clinicians neglect most. Building these in early — rather than relying on clinical instinct — is consistently where the marginal pass becomes a comfortable one.

Passing Part 1 unlocks MRCP(UK) Part 2 (written) and PACES (the practical clinical exam). Completing all three confers MRCP(UK).


MRCP Part 1 Format: Two Papers, 200 Questions

Both papers are sat on the same day, so stamina and pacing matter as much as knowledge.

The Papers
Best-of-Five (BOF)
Questions2 × 100 = 200
Duration2 × 3 hours
FormatOne stem, five options
Negative markingNone
Choose the single best answer from five plausible options — testing applied reasoning, not recall.
Standard & Result
Criterion-Referenced
Pass markStandard-set
Typical region~55–65%
Attempts allowedMaximum 6
Sittings3 per year
The pass mark is set by the Hofstee and Angoff methods against paper difficulty, so it shifts slightly each diet.
✓ No negative marking — answer everything

Every question deserves an answer. With no penalty for wrong responses, an educated guess on a tough item is always better than a blank.


MRCP Part 1 High-Yield Topics

Coverage spans the whole of general medicine plus the clinical sciences. Marks cluster around the major medical specialties and the science that underpins them.

Highest-Yield Areas

  • Clinical Pharmacology & Therapeutics: mechanisms, interactions, adverse effects, pharmacokinetics — woven through every specialty.
  • Cardiology: ECG and arrhythmia interpretation, heart failure, valvular disease, inherited conditions.
  • Endocrinology & Metabolic: pituitary and adrenal axes, thyroid, calcium, diabetes complications.
  • Gastroenterology & Hepatology: liver disease, IBD, malabsorption, GI physiology.
  • Nephrology: acid–base, electrolytes, glomerular disease, AKI and CKD.
  • Haematology & Infectious Diseases: anaemias, clotting, malignancy, antimicrobials and tropical disease.
  • Clinical Sciences: cell and molecular biology, genetics, immunology, physiology and statistics — the most under-prepared, high-yield block.
💡 Don't skip the statistics

Medical statistics and study design appear every sitting and are quick marks once learned. A few hours on sensitivity, specificity, predictive values and relative risk pays off disproportionately.


How to Prepare for MRCP Part 1

Most candidates working full-time need 3 to 6 months. The plan below is question-led — the most efficient route to a pass. See our MRCP guides on the MedLumen blog.

Month 1 · Foundations
Clinical sciences, pharmacology and statistics first
Front-load the under-prepared blocks while motivation is highest. Do focused questions on pharmacology, immunology, genetics and stats, reviewing every explanation. These are reliable, learnable marks.
Month 2–3 · System Sweep
Specialty-by-specialty best-of-five practice
Work cardiology, endocrine, gastro, renal, neuro, rheumatology, haematology and ID in timed blocks. Let the analytics dashboard target your weakest systems automatically.
Month 4–5 · Mocks & Consolidation
Full timed mock papers under exam conditions
Sit full-length mocks to build the stamina for two 3-hour papers in a day. Review each mock thoroughly and re-drill the topics that cost you marks.
Final 2 Weeks · Targeted Review
Weak areas and bookmarks only
Drill your three lowest-accuracy areas, review bookmarked questions, and rest in the final 48 hours. No new content.

Why MedLumen for MRCP Part 1?

🤖
AI Adaptive Selection
Questions that expose your gaps appear more often, so every session targets where your score can rise fastest across the blueprint.
📊
Analytics by Specialty
Track accuracy in every specialty and the clinical sciences, with a projected standing relative to the pass mark.
📱
iOS & Android App
Practise on the iOS app or Android app, synced across devices.
📋
Full Mock Papers
Timed two-paper mocks that replicate the real exam day's pace and pressure.
📖
Detailed Explanations
Every answer is explained with the underlying science and current guideline reasoning — so you learn the why.
🔄
Unlimited Resets
Reset and start fresh as many times as you need across multiple sittings.

MRCP Part 1 Curriculum Coverage

The question bank spans the full MRCP(UK) blueprint. Explore by area:


MRCP Part 1 Question Bank Pricing

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Frequently Asked Questions About MRCP Part 1

What is the MRCP Part 1 exam?
MRCP(UK) Part 1 is the first of three assessments in the Membership of the Royal Colleges of Physicians exam, run by the Federation of Royal Colleges of Physicians. It tests applied basic and clinical sciences across general medicine, as two 3-hour papers of 100 best-of-five questions each on the same day.
How many questions are in MRCP Part 1?
200 best-of-five questions total — two papers of 100, three hours each. One stem, five options, single best answer, with no negative marking.
What is the MRCP Part 1 pass mark?
It is criterion-referenced (Hofstee and Angoff), so it varies with paper difficulty — typically around 55–65%. First-attempt pass rates are historically ~40–55%.
Who is eligible to sit MRCP Part 1?
A recognised primary medical qualification and at least 12 months of postgraduate medical experience by the exam date. You don't need to work in the UK. Maximum six attempts.
What topics does MRCP Part 1 cover?
All major medical specialties plus clinical pharmacology and the clinical sciences (cell/molecular biology, genetics, immunology, physiology, statistics). Pharmacology and clinical sciences are heavily weighted and commonly under-prepared.
How long should I prepare?
Usually 3–6 months alongside work. Go question-led, front-load the sciences and pharmacology, and finish with full timed mock papers to build day-long stamina.
Is there negative marking?
No. Always answer every question — an educated guess can only help.
Is there a free MRCP Part 1 trial?
Yes — a 7-day free trial with full access to the question bank, mock papers and analytics, no card required.
What comes after Part 1?
MRCP(UK) Part 2 (written) and PACES (clinical). All three together confer MRCP(UK), a key requirement for higher specialty training.

Start Your MRCP Part 1 Preparation Today

Best-of-five practice across the full MRCP(UK) blueprint, with mocks and AI analytics. Free 7-day trial.

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