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Master Specialist Family Medicine (FAM5871)
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Sample Practice Questions

Question 1 FULLY WORKED EXAMPLE

A 58-year-old man with type 2 diabetes and a 6-month history of burning epigastric pain relieved by food presents to your clinic. He has no alarm features, no NSAID use, and no prior GI history. His eGFR is 28 mL/min/1.73 m? (CKD stage 4). You decide to test for Helicobacter pylori and initiate empirical acid suppression while awaiting results. Which is the most appropriate initial acid-suppressing agent?

A) Omeprazole 20 mg once daily
B) Ranitidine 150 mg twice daily
C) Famotidine 20 mg once daily ✓ Correct
D) Esomeprazole 40 mg once daily
Explanation:
The deciding finding is the eGFR of 28 mL/min/1.73 m?, indicating advanced CKD. Proton pump inhibitors (PPIs) are generally preferred for H. pylori-related dyspepsia and peptic ulcer disease, but in severe renal impairment, PPIs require dose adjustment and carry a risk of acute interstitial nephritis and worsening renal function; famotidine, an H2 receptor antagonist, is renally cleared and requires dose reduction but is the safer first-line choice in this context per the KDIGO and NICE CKD guidance. Omeprazole and esomeprazole are PPIs that accumulate in renal impairment and are not the preferred initial agents when eGFR is below 30. Ranitidine was withdrawn from the market in many countries due to NDMA contamination and is no longer a recommended option. Famotidine at a reduced dose is appropriate and does not require the same caution as PPIs in advanced CKD.
References: NICE Guideline: Chronic kidney disease: assessment and management (NG203), topic: drug prescribing in CKD.
Question 2 TRY IT — TAP AN ANSWER

A 34-year-old woman at 10 weeks' gestation presents with a 3-day history of dysuria, urinary frequency, and suprapubic discomfort. She is afebrile, has no flank pain, and a urine dipstick shows nitrites and leukocytes. She has no allergies. Which is the most appropriate antibiotic?

A) Ciprofloxacin 500 mg twice daily for 7 days
B) Nitrofurantoin 100 mg twice daily for 5 days
C) Trimethoprim 200 mg twice daily for 7 days
D) Amoxicillin 500 mg three times daily for 7 days
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Question 3 TRY IT — TAP AN ANSWER

A 72-year-old man with hypertension and osteoarthritis presents with a 2-week history of bilateral ankle swelling and dyspnoea on exertion. He takes amlodipine 10 mg daily and ibuprofen 400 mg three times daily. His BP is 148/88 mmHg, pulse 78/min, and JVP is elevated. Echocardiogram shows preserved ejection fraction (EF 58%) and grade II diastolic dysfunction. Which is the most appropriate first step in management?

A) Increase amlodipine to 10 mg twice daily
B) Add furosemide 40 mg once daily
C) Stop ibuprofen and add a loop diuretic if symptoms persist
D) Start bisoprolol 2.5 mg once daily
💡 Pick an answer above to see if you're right — the full explanation unlocks instantly.
Question 4 TRY IT — TAP AN ANSWER

A 45-year-old woman with a BMI of 32 kg/m? and no other comorbidities presents with a 3-month history of polyuria, polydipsia, and fatigue. Fasting plasma glucose is 7.8 mmol/L and HbA1c is 7.2% (54 mmol/mol). She has no contraindications. According to NICE, which is the most appropriate first-line pharmacological treatment?

A) Metformin 500 mg once daily titrated upwards
B) Gliclazide 40 mg once daily
C) Pioglitazone 15 mg once daily
D) Empagliflozin 10 mg once daily
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Question 5 TRY IT — TAP AN ANSWER

A 28-year-old woman presents with a 4-day history of severe left-sided headache, photophobia, and nausea. She has a history of migraine with aura and is currently 8 weeks pregnant. She has already tried paracetamol 1 g without relief. Which is the most appropriate acute treatment?

A) Sumatriptan 50 mg orally
B) Ibuprofen 400 mg orally
C) Metoclopramide 10 mg orally plus paracetamol 1 g
D) Ergotamine 1 mg orally
💡 Pick an answer above to see if you're right — the full explanation unlocks instantly.

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Specialist Family Medicine (FAM5871) Questions for DHA Speciality — FAQ

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MedLumen currently has 253+ Specialist Family Medicine (FAM5871) practice questions for DHA Speciality, each with a detailed explanation so you understand the reasoning behind every answer.

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