Master Paediatrics
for PLAB 1
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Core Concepts
Paediatrics focuses on the health and medical care of infants, children, and adolescents. Key areas include understanding normal growth and development (milestones, growth charts), the importance of routine immunisation schedules, and recognising the spectrum of common childhood illnesses. A crucial aspect is child safeguarding, identifying and acting upon concerns of non-accidental injury (NAI) or neglect. Neonatology covers the unique challenges of newborns, including prematurity, neonatal jaundice, and sepsis. Paediatric emergencies like sepsis, asthma exacerbations, anaphylaxis, and apparent life-threatening events (ALTEs)/brief resolved unexplained events (BRUEs) require prompt recognition and management.
Clinical Presentation
- History Taking: Always include presenting complaint (PC), history of presenting complaint (HPC) covering ICE (Ideas, Concerns, Expectations), relevant past medical history (PMH), drug history (DH), allergies (AH), family history (FH), and social history (SH). Specifically for paediatrics, inquire about birth history, developmental milestones, feeding, immunisation status, and safeguarding concerns.
- Symptoms:
- Fever: Common, assess for associated symptoms (rash, vomiting, lethargy, work of breathing).
- Respiratory: Cough, wheeze, stridor, shortness of breath, grunting (e.g., bronchiolitis, asthma, croup, pneumonia).
- Gastrointestinal: Vomiting, diarrhoea, abdominal pain, poor feeding (e.g., gastroenteritis, appendicitis, intussusception).
- Rashes: Characterise type, distribution, blanching status (e.g., viral exanthems, meningococcal rash, purpura, eczema).
- Developmental Delay: Concerns regarding motor, speech, social, or cognitive milestones.
- Irritability/Lethargy: Non-specific but concerning, especially in infants.
- Examination: Begin with general observation (alertness, colour, hydration, respiratory effort). Systemic examination focusing on vital signs (HR, RR, T, BP, SpO2), growth parameters (weight, height, head circumference plotted on centile charts), and relevant system examination (e.g., chest auscultation, abdominal palpation, neurological assessment including fontanelles).
Diagnosis (Gold Standard)
Diagnosis in paediatrics often relies heavily on clinical assessment supported by targeted investigations. For many common conditions (e.g., bronchiolitis, viral exanthems, gastroenteritis), the diagnosis is purely clinical. For suspected infections like sepsis, the gold standard involves blood cultures, alongside FBC, CRP, lactate, and urine MC&S; CSF analysis for meningitis. UTI is diagnosed by urine dipstick and MC&S. Developmental delay often requires formal assessment by a paediatrician and may involve genetic testing or neuroimaging. Child abuse investigations necessitate a thorough history, physical examination, skeletal survey (X-rays), and ophthalmological assessment.
Management (First Line)
First-line management in paediatrics prioritises supportive care and addressing emergencies. The ABCDE approach is crucial for acutely unwell children. Hydration (oral rehydration solution for mild-moderate dehydration, IV fluids for severe), antipyretics (paracetamol/ibuprofen), and pain relief are fundamental. Specific treatments include: salbutamol and oral steroids for asthma exacerbations; adrenaline for anaphylaxis; broad-spectrum IV antibiotics and fluid resuscitation for suspected sepsis; nebulised adrenaline and dexamethasone for croup; supportive care with oxygen and nasogastric feeds for bronchiolitis; phototherapy for significant neonatal jaundice; and age-appropriate antibiotics for UTI. Always ensure immunisation status is up-to-date. For safeguarding concerns, immediate documentation and referral to social services are paramount.
Exam Red Flags
- Non-blanching rash (petechiae/purpura): Urgent assessment for meningococcal sepsis.
- Lethargy, poor feeding, irritability, floppy tone in an infant: High suspicion for sepsis.
- Severe work of breathing (grunting, subcostal/intercostal recession, nasal flaring, tachypnoea): Respiratory distress, potentially severe infection or asthma exacerbation.
- Bulging fontanelle: Raised intracranial pressure (e.g., meningitis, hydrocephalus).
- Significant dehydration signs: Sunken eyes, reduced skin turgor, prolonged capillary refill time, decreased urine output – requires urgent fluid resuscitation.
- Inconsistent history, unexplained injuries, multiple injuries of varying ages, or parental delay in seeking care: Suspect Non-Accidental Injury (NAI) or child abuse.
- Fever for >5 days with rash, conjunctivitis, red lips/tongue, swollen hands/feet, cervical lymphadenopathy: Kawasaki disease (risk of coronary artery aneurysms).
- ALTE/BRUE (Apparent Life-Threatening Event / Brief Resolved Unexplained Event): Always requires thorough investigation to rule out serious underlying causes.
- Stridor in a febrile child: Consider epiglottitis (rare due to HiB vaccine) or severe croup.
Sample Practice Questions
A 3-day-old term baby, exclusively breastfed, presents with yellow discolouration of the skin and sclera. The jaundice was first noticed yesterday. The baby is active, feeding well (8-10 feeds/day), passing urine and stools regularly. Weight loss since birth is 5%. Physical examination is otherwise normal, and there is no hepatosplenomegaly.
An 18-month-old boy presents to the emergency department after experiencing a brief, generalised tonic-clonic seizure lasting approximately 2 minutes. His parents report he had a temperature of 39.5°C before the seizure, and he has a runny nose and cough. He is now alert, a little drowsy, but otherwise recovering well. He has no prior history of seizures. What is the most appropriate initial advice to give the parents?
A 3-year-old boy presents to the emergency department with sudden onset of severe, colicky abdominal pain, accompanied by episodes of non-bilious vomiting. His parents report that he has passed a stool that looks like 'redcurrant jelly'. On examination, he is pale and lethargic, with a palpable sausage-shaped mass in the right upper quadrant. What is the most likely diagnosis?
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