Master General Surgery
for SMLE
Access 50+ high-yield questions tailored for the 2026 syllabus. Includes AI-powered explanations and performance tracking.
Core Concepts
- **Scope:** Diagnosis & management of diseases involving the GI tract (esophagus to rectum), endocrine glands (thyroid, parathyroid, adrenal, pancreas), breast, soft tissues, vascular system, and acute surgical conditions (trauma, critical care).
- **Key Principles:**
- **Acute vs. Elective:** Differentiate urgent surgical emergencies from planned procedures.
- **Sterile Technique:** Fundamental for preventing surgical site infections.
- **Pre-operative Assessment:** Optimize patient health to minimize risks (cardiac, pulmonary, renal, nutrition, NPO, DVT/antibiotic prophylaxis).
- **Post-operative Care:** Pain management, fluid balance, early mobilization, monitoring for complications (bleeding, infection, DVT/PE, ileus, anastomotic leak).
- **Shock & Resuscitation:** Recognize and manage hypovolemic, septic, cardiogenic, obstructive shock (ATLS principles for trauma).
Clinical Presentation
- **Acute Abdomen:** Sudden severe abdominal pain.
- **Appendicitis:** Periumbilical pain migrating to RIF, anorexia, N/V, fever, McBurney's tenderness.
- **Acute Cholecystitis:** RUQ pain radiating to R shoulder/back, fever, N/V, positive Murphy's sign.
- **Diverticulitis:** LLQ pain, fever, altered bowel habits (often elderly).
- **Small Bowel Obstruction (SBO):** Colicky pain, vomiting, distension, absolute constipation, tinkling bowel sounds.
- **Perforated Viscus (e.g., Peptic Ulcer):** Sudden, severe, generalized abdominal pain, guarding, "board-like" rigidity.
- **Acute Pancreatitis:** Severe epigastric pain radiating to back, N/V.
- **Ruptured AAA:** Sudden severe back/abdominal pain, hypotension, pulsatile abdominal mass.
- **Gastrointestinal Bleeding:** Hematemesis/melena (UGI), hematochezia (LGI).
- **Hernias:** Palpable bulge; pain, irreducibility, or strangulation signs (erythema, systemic toxicity) are critical.
- **Breast Lumps:** Palpable mass, skin changes (peau d'orange), nipple discharge/retraction.
- **Thyroid Pathology:** Neck lump/swelling (goiter), dysphagia, dyspnea, hoarseness, +/- hypo/hyperthyroid symptoms.
- **Trauma:** Injuries following blunt/penetrating force; focus on ABCDE assessment.
- **Surgical Infections:** Localized pain, swelling, redness, warmth, fever (e.g., abscesses, cellulitis, necrotizing fasciitis).
- **Vascular:**
- **Peripheral Arterial Disease (PAD):** Intermittent claudication, rest pain, trophic changes, non-healing ulcers.
- **Deep Vein Thrombosis (DVT):** Leg pain, swelling, tenderness, warmth, erythema.
Diagnosis (Gold Standard)
- **History & Physical Examination:** Always the first and most crucial step.
- **Laboratory Tests:** CBC (leukocytosis, anemia), U&E, LFT, Amylase/Lipase, Coagulation profile, G&S, ABG.
- **Imaging:**
- **Plain Radiographs (CXR/AXR):** CXR: free air under diaphragm (perforation). AXR: dilated bowel loops, air-fluid levels (SBO).
- **Ultrasound (US):** Highly useful for gallstones/cholecystitis, appendicitis (peds/pregnant), AAA, DVT, breast lumps, thyroid nodules.
- **Computed Tomography (CT) Scan:** **Often gold standard for acute abdomen** (appendicitis, diverticulitis, perforation, AAA, trauma assessment, staging malignancy). CT angiography for vascular disease.
- **Endoscopy (EGD/Colonoscopy):** Gold standard for diagnosing and often treating GI bleeding, strictures, masses.
- **Biopsy (Histopathology):** **Definitive for malignancy** (breast, thyroid, GI masses).
- **Angiography:** Gold standard for vascular lesions (PAD, acute ischemia).
Management (First Line)
- **Resuscitation & Stabilization:**
- **ABCDE Assessment:** Prioritize airway, breathing, circulation.
- **IV Fluids:** Crystalloids (e.g., Normal Saline, Ringer's Lactate) for hypovolemia/shock.
- **Oxygen:** Supplemental O2 for hypoxia.
- **Analgesia:** Early pain control (e.g., opioids).
- **NPO & Nasogastric Tube (NGT):** For bowel obstruction, pancreatitis, pre-op.
- **Antibiotics:** Empiric broad-spectrum for suspected infection (e.g., intra-abdominal sepsis, diverticulitis, cholecystitis) or prophylaxis.
- **Specific Surgical Interventions:**
- **Acute Appendicitis/Cholecystitis:** Laparoscopic appendectomy/cholecystectomy.
- **Perforated Viscus:** Emergency exploratory laparotomy with primary repair or resection.
- **Small Bowel Obstruction (SBO):** Initial conservative management (NPO, NGT, IV fluids); surgical lysis of adhesions or resection for strangulation/failure of conservative Rx.
- **Hernia:** Elective repair (herniorrhaphy/hernioplasty); emergency repair for incarcerated/strangulated hernias.
- **GI Bleeding:** Endoscopic intervention (clipping, coagulation) often first line; surgical exploration for refractory bleeding.
- **Breast/Thyroid Cancer:** Surgical resection (mastectomy/thyroidectomy) + adjuvant therapy.
- **Trauma:** Damage control surgery for severe trauma, specific repairs based on injury.
- **Abscess:** Incision and drainage (I&D).
- **PAD:** Revascularization (angioplasty/stenting, bypass surgery) for critical limb ischemia.
- **DVT:** Anticoagulation (heparin followed by warfarin/DOACs).
Exam Red Flags
- **Peritonitis (Generalized Rigidity, Rebound Tenderness):** Suggests diffuse intra-abdominal inflammation/perforation, requires urgent surgical exploration.
- **Hemodynamic Instability/Shock:** Hypotension, tachycardia, altered mental status, indicates severe pathology (e.g., hemorrhage, sepsis) requiring immediate resuscitation and likely surgery.
- **Strangulated Hernia:** Painful, irreducible hernia with skin changes and systemic toxicity (fever, leukocytosis). **Surgical emergency** due to bowel ischemia.
- **Necrotizing Soft Tissue Infection (e.g., Necrotizing Fasciitis):** Severe pain out of proportion to exam, rapidly spreading erythema, crepitus, systemic toxicity. Requires **urgent radical debridement**.
- **Acute Limb Ischemia:** Sudden onset of "6 Ps": Pain, Pallor, Pulselessness, Paresthesia, Paralysis, Poikilothermia. **Surgical emergency** to prevent limb loss.
- **Ruptured Abdominal Aortic Aneurysm (AAA):** Sudden severe abdominal/back pain, pulsatile mass, hypotension. **Life-threatening emergency**, requires immediate transport to OR.
- **Septic Shock unresponsive to initial resuscitation:** Indicates ongoing source of infection that needs surgical control (drainage, debridement, resection).
Sample Practice Questions
A 68-year-old male presents with a several-month history of a reducible bulge in his right groin that becomes more prominent with coughing or straining. He reports occasional mild discomfort but no severe pain. On examination, a soft, non-tender mass is palpable in the right inguinal region, which disappears when he lies down. What is the most appropriate definitive management for this patient?
A 60-year-old male presents with a 2-day history of left lower quadrant abdominal pain, fever (38.5ยฐC), and mild nausea. He reports alternating constipation and diarrhea over the past week. On examination, there is localized tenderness in the left lower quadrant without rebound or guarding. His white blood cell count is 14,000/ยตL. A CT scan of the abdomen confirms acute uncomplicated diverticulitis with no evidence of perforation or abscess. What is the most appropriate initial management?
A 55-year-old male is brought to the emergency department after a sudden episode of massive hematemesis. He is conscious but drowsy. His blood pressure is 80/50 mmHg, heart rate is 120 bpm, and respiratory rate is 22 breaths/min. His skin is cool and clammy. He has a history of chronic alcohol abuse and takes NSAIDs for osteoarthritis.
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