Master Family Medicine
for SMLE
Access 50+ high-yield questions tailored for the 2026 syllabus. Includes AI-powered explanations and performance tracking.
What the SMLE Tests in Family Medicine
Family Medicine on the SMLE tests the ability to manage undifferentiated presentations across all ages in a community setting, with emphasis on chronic disease monitoring, acute infection management, preventive care, and appropriate referral. Candidates must demonstrate knowledge of evidence-based screening intervals (e.g., cervical smear every 3–5 years, abdominal aortic aneurysm ultrasound once at age 65 for men), first-line pharmacotherapy for common conditions (e.g., metformin for type 2 diabetes, ACE inhibitors for hypertension with CKD), and recognition of red flags requiring urgent specialist input (e.g., unilateral headache with jaw claudication for giant cell arteritis). The exam also assesses understanding of UK-style QOF targets (e.g., HbA1c ≤ 58 mmol/mol in diabetes, BP ≤ 140/90 in CKD) and appropriate use of scoring systems (e.g., CURB-65 for pneumonia, ABCD2 for TIA risk).
High-Yield Concepts
- Hypertension management in primary care: First-line for age <55: ACE inhibitor (ramipril 2.5 mg) or ARB. For age ≥55 or black patients: calcium channel blocker (amlodipine 5 mg). Target clinic BP <140/90 (or <130/80 if CKD, diabetes, or CVD). Offer ambulatory BP monitoring to confirm diagnosis if clinic BP ≥140/90.
- Type 2 diabetes monitoring and targets: HbA1c target ≤ 53 mmol/mol (7%) for most; ≤ 58 mmol/mol (7.5%) if on sulfonylurea/insulin or frail. First-line metformin (start 500 mg once daily, titrate to 2 g). Annual foot check (monofilament + pulses), retinal screening, and urine ACR for nephropathy.
- Acute sore throat: Centor criteria and antibiotics: Centor criteria: fever >38°C, tonsillar exudate, tender cervical nodes, absence of cough. Score ≥3: consider rapid strep test or treat with phenoxymethylpenicillin 500 mg QDS for 10 days. Avoid amoxicillin if glandular fever suspected (rash risk).
- COPD exacerbation management: Increase bronchodilator (salbutamol via spacer) and start prednisolone 30 mg once daily for 5 days. Add doxycycline 200 mg stat then 100 mg daily for 5 days if purulent sputum and clinical signs of infection. Refer if pH <7.35 or PaO2 <8 kPa on ABG.
- Childhood immunisation schedule (UK): 8 weeks: 6-in-1 (DTaP/IPV/Hib/HepB), rotavirus, MenB. 12 weeks: 6-in-1 second dose, pneumococcal (PCV13). 16 weeks: 6-in-1 third dose, MenB second, rotavirus second. 1 year: Hib/MenC, MMR, PCV13 booster, MenB booster. 3 years 4 months: MMR second, DTaP/IPV preschool.
- Depression screening and first-line treatment: Use PHQ-9 for severity (score ≥10 suggests major depression). First-line: SSRI (sertraline 50 mg daily or fluoxetine 20 mg daily). Warn of initial anxiety and 2-week lag. Review at 2 weeks (suicide risk) and 4 weeks. Refer to IAPT if mild to moderate; refer to CMHT if severe with psychosis or high suicide risk.
- Abdominal aortic aneurysm screening: One-time ultrasound for men aged 65. If AAA 3.0–4.4 cm: annual surveillance. If 4.5–5.4 cm: 3-monthly. Refer to vascular surgery if ≥5.5 cm (or rapid expansion >1 cm/year). Women not routinely screened, but consider if risk factors (smoking, FH).
- Antenatal screening and common issues: Offer combined screening (NT + bloods) at 11–14 weeks for Down’s, Edwards’, Patau’s. Oral glucose tolerance test at 24–28 weeks if BMI >30 or previous GDM. Treat GDM with metformin or insulin if needed. For nausea: first-line cyclizine 50 mg TDS or prochlorperazine 5 mg TDS.
Common Traps in Family Medicine Questions
- Confusing NICE hypertension targets (clinic <140/90) with ABPM targets (daytime average <135/85).
- Using amoxicillin for sore throat without checking glandular fever risk in young adults (causes rash).
- Starting antidepressant at too high a dose (e.g., sertraline 100 mg) without a 2-week titration, increasing side effects and dropout.
- Forgetting to check urine ACR annually in all diabetics, not just those with hypertension.
- Recommending aspirin for primary prevention in type 2 diabetes without assessing bleeding risk (no longer routine per NICE).
- Interpreting PHQ-9 score alone without considering functional impairment and risk of self-harm.
How to Revise Family Medicine for the SMLE
For Family Medicine on the SMLE, prioritise memorising specific numerical targets (BP, HbA1c, cholesterol, eGFR thresholds) and first-line drug choices by age/ethnicity. Questions often present a clinical vignette with a single abnormal value (e.g., BP 148/92 in a 60-year-old) and ask for the next appropriate step—not just diagnosis but whether to repeat, monitor, or start treatment. Practise applying screening intervals (e.g., when to start mammography at age 50, stop at 71) and recognising red flags in common presentations (e.g., headache with vomiting and papilloedema for raised ICP). Focus on UK guidelines (NICE, SIGN) and avoid US-centric cut-offs. Review the QOF registers and annual review checklists for diabetes, COPD, and CKD, as these are frequently used as question frameworks.
Practise it: MedLumen has 50 Family Medicine questions for the SMLE, each with a full explanation and references.
Sample Practice Questions
A 45-year-old female presents to her family physician for an annual health check-up. She has no chronic medical conditions and takes no regular medications. Her mother had breast cancer at age 52, and her paternal grandmother had colon cancer at age 65. The patient expresses concern about her cancer risk. Which of the following is the most appropriate initial screening recommendation for this patient regarding breast cancer?
A 68-year-old male with a history of hypertension and type 2 diabetes mellitus presents with worsening fatigue, shortness of breath on exertion, and ankle swelling. His blood pressure is 150/90 mmHg, heart rate 92 bpm, and oxygen saturation 94% on room air. Jugular venous distension is present, and lung auscultation reveals bilateral basal crackles. What is the most likely diagnosis?
A 3-year-old child is brought to the clinic by his mother with a history of recurrent ear infections, coughing spells, and poor weight gain. He was born prematurely at 32 weeks gestation. On examination, he appears thin for his age, and pulmonary auscultation reveals diffuse crackles and wheezes. Sweat chloride test is performed and is positive. Which of the following is the most appropriate initial management step for this patient?
A 28-year-old male presents with sudden onset of severe, unilateral testicular pain accompanied by nausea and vomiting. On examination, the affected testicle is exquisitely tender, high-riding, and has an absent cremasteric reflex. Doppler ultrasound shows absent blood flow to the affected testicle. What is the most urgent next step in management?
A 55-year-old male with a history of uncontrolled type 2 diabetes mellitus (HbA1c 9.5%) and dyslipidemia presents for routine follow-up. He reports occasional numbness and tingling in his feet, particularly at night. On examination, he has diminished sensation to light touch and vibration in a 'stocking-glove' distribution. Which of the following medications is most appropriate to initiate or optimize for preventing progression of this complication?
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Family Medicine Questions for SMLE — FAQ
How many Family Medicine questions does MedLumen have for SMLE?
MedLumen currently has 50+ Family Medicine practice questions for SMLE, each with a detailed explanation so you understand the reasoning behind every answer.
Are the Family Medicine questions updated for the 2026 SMLE syllabus?
Yes. Our Family Medicine questions are mapped to the latest SMLE blueprint and reviewed regularly so they stay aligned with the current 2026 syllabus.
Can I practise Family Medicine questions for free?
You can preview sample Family Medicine questions for free. A MedLumen subscription unlocks all 50+ Family Medicine questions, full answer explanations, and performance analytics for SMLE.
How should I revise Family Medicine for SMLE?
Practise Family Medicine questions in timed blocks, read the explanation for every answer (right or wrong), and use MedLumen's analytics to revisit your weak areas until your accuracy is consistently high.