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Core Concepts

Pediatrics encompasses health and medical care for infants, children, and adolescents. Key areas include preventative care, growth and development monitoring, immunizations, and management of acute and chronic diseases. Growth charts (WHO for 0-5 years, CDC for >2 years) are essential for tracking physical development. Developmental milestones (gross motor, fine motor, language, social) must be assessed regularly, with delays prompting further investigation (e.g., Denver II, ASQ-3). Immunization schedules are crucial for disease prevention (e.g., DTaP, Polio, Hib, PCV, MMR, Varicella, Hep B, Rotavirus). Newborn screening (Guthrie test for metabolic disorders like PKU, G6PD, Hypothyroidism; hearing screen; critical congenital heart disease screen using pulse oximetry) is vital. Ethical considerations in pediatric practice involve parental consent, child assent (when appropriate), confidentiality, and safeguarding.

Clinical Presentation

  • Respiratory:
    • Bronchiolitis (infants <2y): Viral prodrome, wheezing, cough, tachypnea, retractions. RSV common.
    • Asthma: Recurrent cough, wheezing, shortness of breath, chest tightness, often triggered.
    • Croup (Laryngotracheobronchitis): Barking cough, inspiratory stridor, hoarseness. Viral aetiology.
    • Pneumonia: Fever, cough, tachypnea, increased work of breathing, crackles/diminished breath sounds.
  • Gastrointestinal:
    • Gastroenteritis: Vomiting, diarrhea (watery/bloody), fever, dehydration. Viral most common.
    • Pyloric Stenosis (infants 2-8 wks): Projectile non-bilious vomiting, visible peristalsis, olive-shaped mass.
    • Intussusception (infants 3-12 mos): Sudden onset intermittent colicky abdominal pain, 'currant jelly' stool, sausage-shaped mass.
  • Neurological:
    • Febrile Seizures (6 mos-5 yrs): Generalized tonic-clonic seizure during febrile illness, no CNS infection.
    • Meningitis: Fever, headache, neck stiffness, photophobia, lethargy, irritability, non-blanching rash (meningococcal).
  • Cardiac:
    • Congenital Heart Disease: Murmur, cyanosis, poor feeding, failure to thrive, tachypnea, sweating with feeds.
  • Renal/Urinary:
    • UTI: Fever (unexplained in infants), dysuria, frequency, urgency, abdominal/flank pain.
  • Infectious Diseases:
    • Common Childhood Rashes: Measles (Koplik spots, maculopapular rash spreading cephalocaudal), Rubella (milder, postauricular LAD), Varicella (pruritic vesicles 'dewdrops on a rose petal').

Diagnosis (Gold Standard)

Clinical assessment, history, and physical examination are paramount. Specific diagnostic tests include:

  • **Growth/Development:** WHO/CDC charts, Denver II/ASQ-3.
  • **Respiratory:** CXR for pneumonia, spirometry for asthma (if age-appropriate), nasopharyngeal aspirate for RSV/viral PCR in bronchiolitis.
  • **Gastrointestinal:** Abdominal ultrasound for pyloric stenosis, air/barium enema for intussusception (diagnostic & therapeutic). Stool culture/PCR for persistent gastroenteritis.
  • **Neurological:** Lumbar puncture for suspected meningitis (CSF analysis, culture, PCR). EEG for recurrent seizures.
  • **Cardiac:** Echocardiography for congenital heart disease.
  • **Renal/Urinary:** Urine culture (suprapubic aspirate/catheter sample preferred in infants/young children) for UTI.
  • **Hematology:** CBC for anemia (e.g., Iron Deficiency Anemia).

Management (First Line)

Management principles often involve supportive care, symptom control, and targeted interventions:

  • **General:** ABCs (Airway, Breathing, Circulation), IV fluids for dehydration, antipyretics for fever.
  • **Respiratory:**
    • Bronchiolitis: Supportive care (hydration, oxygen if SpO2 <90%), nasal suctioning. No routine bronchodilators/steroids.
    • Asthma: Short-acting beta-agonists (SABA) for acute attacks, inhaled corticosteroids (ICS) for maintenance.
    • Croup: Dexamethasone (oral single dose), nebulized adrenaline for moderate-severe.
    • Pneumonia: Amoxicillin (first-line for community-acquired bacterial pneumonia).
  • **Gastrointestinal:**
    • Gastroenteritis: Oral rehydration therapy (ORT), antiemetics (ondansetron) if severe vomiting, zinc supplementation (WHO/UNICEF recommendation).
    • Pyloric Stenosis: Pyloromyotomy (surgical).
    • Intussusception: Air/barium enema (therapeutic). Surgical reduction if enema fails.
  • **Neurological:**
    • Febrile Seizures: Reassurance, manage fever, no routine anticonvulsants.
    • Meningitis: Empirical IV antibiotics (e.g., Ceftriaxone) immediately after LP or blood cultures if LP delayed, plus dexamethasone in bacterial meningitis.
  • **Renal/Urinary:** UTI: Oral antibiotics (e.g., co-amoxiclav, trimethoprim-sulfamethoxazole) after urine culture.
  • **Preventative:** Adherence to national immunization schedules.

Exam Red Flags

  • Severe Respiratory Distress: Grunting, nasal flaring, subcostal/intercostal retractions, cyanosis, diminished breath sounds, severe tachypnea.
  • Signs of Meningitis/Sepsis: Non-blanching rash (purpura/petechiae), lethargy, altered mental status, high-pitched cry, bulging fontanelle (infants), neck stiffness, fever with cold extremities.
  • Dehydration: Sunken fontanelle, sunken eyes, dry mucous membranes, poor skin turgor, reduced urine output, lethargy/irritability.
  • Non-Accidental Injury (NAI) Suspicions: Bruises/fractures in non-mobile infants, injuries inconsistent with history, cigarette burns, retinal hemorrhages, multiple fractures of different ages.
  • Abdominal Emergencies: Bilious vomiting (always pathological), severe abdominal distension with guarding/rebound tenderness, sudden severe episodic abdominal pain, absent bowel sounds.
  • Developmental Delays: Loss of previously acquired milestones, or significant failure to achieve age-appropriate milestones (e.g., not walking by 18 months, no babbling by 12 months, no words by 18 months).
  • Anaphylaxis: Sudden onset generalized rash, facial/lip swelling, stridor, wheezing, hypotension after exposure to allergen.

Sample Practice Questions

Question 1

A 3-day-old full-term infant presents to the clinic with jaundice. He was delivered vaginally, had Apgar scores of 9 and 9, and is breastfed exclusively. His mother is Rh-positive, and the infant's blood type is B-positive. Physical examination reveals yellow discoloration of the skin extending to the abdomen. Total serum bilirubin (TSB) is 18 mg/dL, with direct bilirubin of 0.8 mg/dL. The infant is alert, feeding well, and has appropriate urine and stool output. What is the most appropriate initial management for this infant?

A) Refer for immediate exchange transfusion.
B) Initiate phototherapy.
C) Reassure the mother and advise continued breastfeeding, with a follow-up in 24 hours.
D) Investigate for hemolytic disease of the newborn.
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Question 2

An 18-month-old boy is brought to the emergency department by his parents after experiencing a brief generalized tonic-clonic seizure that lasted approximately 2 minutes. The seizure occurred while he had a fever of 39.5°C and symptoms of a viral upper respiratory infection. He recovered spontaneously, is now alert, and responds appropriately. There is no history of previous seizures, head trauma, or neurologic abnormalities. Family history is negative for epilepsy. What is the most appropriate advice to give the parents regarding this event?

A) The child requires immediate initiation of long-term antiepileptic medication.
B) This was likely a simple febrile seizure, which is generally benign, and further extensive investigations are usually not required.
C) Lumbar puncture is mandatory to rule out meningitis given the fever and seizure.
D) The child is at high risk of developing epilepsy and should be monitored closely for recurrent seizures.
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Question 3

A 2-year-old boy is brought to the clinic by his parents who are concerned about his development. He uses only 3-4 single words, does not point to objects when asked, and rarely makes eye contact. He prefers to play alone and sometimes engages in repetitive hand flapping.

A) Reassure the parents that boys often develop language later.
B) Advise speech therapy only.
C) Refer for a comprehensive developmental assessment, including an autism spectrum disorder screening.
D) Order a hearing test and brain MRI.
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